BDBM50075667 3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclopent-2-enone::CHEMBL278336

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C#Cc2ccccc2)C(=O)CC1

InChI Key InChIKey=SYCDCMGVFQIMAR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075667   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075667(3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...)
Affinity DataIC50: 6nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075667(3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...)
Affinity DataIC50: 640nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075667(3-(4-Methanesulfonyl-phenyl)-2-phenylethynyl-cyclo...)
Affinity DataIC50: 710nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed