BDBM50075663 2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL428710

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)ccn1

InChI Key InChIKey=DUFCCGCFKPQHHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075663   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075663(2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...)
Affinity DataIC50: 190nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075663(2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...)
Affinity DataIC50: 520nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075663(2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...)
Affinity DataIC50: 3.40E+4nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075663(2-(4-Chloro-pyridin-2-yl)-3-(4-methanesulfonyl-phe...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed