BDBM50075655 3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-phenyl)-cyclopent-2-enone::CHEMBL278392

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cc(Cl)c(Cl)c(Cl)c1

InChI Key InChIKey=ASRZEXHEXSQIBP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075655   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075655(3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-ph...)
Affinity DataIC50: 6nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075655(3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-ph...)
Affinity DataIC50: 930nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075655(3-(4-Methanesulfonyl-phenyl)-2-(3,4,5-trichloro-ph...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed