BDBM50075415 4-(2,4-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid::CHEMBL156404

SMILES COc1ccc(c(OC)c1)-c1c(C(O)=O)c(=O)n(Cc2ccccc2OC)c2c1oc1ccccc21

InChI Key InChIKey=RPKUYMGAJFMAPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075415   

TargetEndothelin-1 receptor(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50075415(4-(2,4-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin A receptor in rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50075415(4-(2,4-Dimethoxy-phenyl)-1-(2-methoxy-benzyl)-2-ox...)
Affinity DataIC50: 430nMAssay Description:Ability to displace [125I]endothelin-1 from endothelin B receptor in porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed