BDBM50075364 2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline::CHEMBL156896

SMILES C(N1CCc2ccccc2C1)c1cc2cccnc2[nH]1

InChI Key InChIKey=ZNJRNDKOAPREMV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075364   

TargetD(4) dopamine receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  59nMAssay Description:Ability to displace [3H]spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  600nMAssay Description:Ability to displace [3H]spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  1.10E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed