BDBM50075321 2-(2,6-Diisopropyl-phenyl)-4-hydroxy-isoindole-1,3-dione::2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3-dione::CHEMBL88474

SMILES CC(C)c1cccc(C(C)C)c1N1C(=O)c2cccc(O)c2C1=O

InChI Key InChIKey=XQXBQIWOUJMXAE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075321   

TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075321(2-(2,6-diisopropylphenyl)-4-hydroxyisoindoline-1,3...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed