BDBM50075318 2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-cyclohex-2-enone::CHEMBL73467

SMILES CS(=O)(=O)c1ccc(c(c1)Cl)C(=O)C2C(=O)CCCC2=O

InChI Key InChIKey=PQTBTIFWAXVEPB-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075318   

Target4-hydroxyphenylpyruvate dioxygenase(Pig)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50: 50nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Pig)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50: 45nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target4-hydroxyphenylpyruvate dioxygenase(Mouse-ear cress)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)