BDBM50075309 CHEMBL150420::[Difluoro-(3-phenylethynyl-phenyl)-methyl]-phosphonic acid

SMILES OP(O)(=O)C(F)(F)c1cccc(c1)C#Cc1ccccc1

InChI Key InChIKey=WLESMKVILQBUJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075309   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075309([Difluoro-(3-phenylethynyl-phenyl)-methyl]-phospho...)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibitory potency for the protein tyrosine phosphatase (PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed