BDBM50075111 2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1-dimethylpropanoic anhydride::CHEMBL134024

SMILES CC(C)(C(NC(=O)c1ccc(cc1)C#N)C1CCC=CC1)C(=O)OC(=O)C(C)(C)C(NC(=O)c1ccc(cc1)C#N)C1CCC=CC1

InChI Key InChIKey=QMMNPJKVOZYGDW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075111   

TargetChymase(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human chymase (h-chymase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 69nMAssay Description:Inhibitory activity against human leukocyte cathepsin G (h-CG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed