BDBM50074920 ((R)-3-Phenyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1-(4-guanidino-benzyl)-2-oxo-propylcarbamoyl]-ethylcarbamoyl}-propyl)-carbamic acid adamantan-1-yl ester

SMILES NC(=[NH2+])Nc1ccc(CC(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCc2ccccc2)NC(=O)OC23CC4CC(CC(C4)C2)C3)C(=O)C(F)(F)F)cc1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074920   

TargetPlasma kallikrein(Human)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074920(((R)-3-Phenyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity of compound against human plasma Kallikrein (PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074920(((R)-3-Phenyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKallikrein-1(Human)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074920(((R)-3-Phenyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibitory activity of compound against Tissue Kallikrein (TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed