BDBM50074918 ((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1-(4-guanidino-benzyl)-2-oxo-propylcarbamoyl]-ethylcarbamoyl}-propyl)-carbamic acid adamantan-1-yl ester

SMILES CC(C)(C)[C@@H](NC(=O)OC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(Cc1ccc(NC(N)=[NH2+])cc1)C(=O)C(F)(F)F

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074918   

TargetPlasma kallikrein(Human)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074918(((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluo...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity of compound against human plasma Kallikrein (PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074918(((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluo...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetKallikrein-1(Human)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074918(((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluo...)
Affinity DataKi:  4.73E+4nMAssay Description:Inhibitory activity of compound against Tissue Kallikrein (TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed