BDBM50074743 3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-one::CHEMBL266995

SMILES Oc1cc(O)c2c(O)c(cnc2c1)-c1cccc(Cl)c1

InChI Key InChIKey=ZDTZOBIXVNHHCR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50074743   

LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed