BDBM50074741 3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-one::CHEMBL7339

SMILES COc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O

InChI Key InChIKey=LDUNOFBTXWMVEY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50074741   

TargetProtein kinase C alpha type(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed