BDBM50074739 3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethyl-1H-quinolin-4-one::CHEMBL7810

SMILES COc1cc(O)c2c(c1)n(CCc1ccccc1)cc(-c1cccc(Cl)c1)c2=O

InChI Key InChIKey=YEELQJLZRMCLAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074739   

LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed