BDBM50074443 CHEMBL169416::[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(1-methoxymethyl-propyl)-amine

SMILES CCC(COC)Nc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C

InChI Key InChIKey=ZHUNFLIPSWZNCN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074443   

TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074443([3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074443([3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074443([3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed