BDBM50074025 3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptanoic acid hydroxyamide::CHEMBL432299

SMILES COc1ccc(cc1OC)S(=O)(=O)C(CCCCc1ccccc1)CC(=O)NO

InChI Key InChIKey=WDJVSROJMOYUQL-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50074025   

Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataIC50: 1.30nMAssay Description:Phosphodiesterase 4 inhibitory activity measured against guinea pig macrophage homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3), stromelysin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2), gelatinase-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074025(3-(3,4-Dimethoxy-benzenesulfonyl)-7-phenyl-heptano...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1), fibroblast collagenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed