BDBM50074011 1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-indene-2,4'-(hexahydropyridine)]-1-one::CHEMBL100052

SMILES O=C1c2ccccc2CC11CCN(CCc2cccc3ccccc23)CC1

InChI Key InChIKey=LXIPAAJKLDMQAA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074011   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  31nMAssay Description:Ability to displace [125I]HEAT from cloned human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  149nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed