BDBM50074005 CHEMBL419164::N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]-7-yl]methanesulfonamide::N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]-7-yl]methanesulfonamide; hydrochloride; hydrate

SMILES CS(=O)(=O)Nc1ccc2C(=O)CC3(CCN(CCc4ccccn4)CC3)Oc2c1

InChI Key InChIKey=SPDFHNLNFIMTBW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074005   

TargetAlpha-1A adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-...)
Affinity DataKi:  1.67E+3nMAssay Description:Ability to displace [125I]HEAT from cloned human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-...)
Affinity DataKi:  3.25E+3nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed