BDBM50073867 CHEMBL287909::N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc2COC(=O)c2cc1Sc1nccs1

InChI Key InChIKey=TVSFBCFQMGXADL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073867   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073867(N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isob...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073867(N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isob...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073867(N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isob...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073867(N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isob...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed