BDBM50073860 CHEMBL434014::N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide

SMILES CSc1csc(Sc2cc3C(=O)OCc3cc2NS(C)(=O)=O)n1

InChI Key InChIKey=FCRDFQWYMOBSIT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073860   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073860(N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073860(N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073860(N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50073860(N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed