BDBM50073828 Benzyl-[2-((R)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-phosphinic acid::CHEMBL27647

SMILES CNC(=O)[C@H](NC(=O)C(CCc1ccccc1)CP(O)(=O)Cc1ccccc1)C(C)(C)C

InChI Key InChIKey=ROFAQOFULLWONA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073828   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50073828(Benzyl-[2-((R)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50073828(Benzyl-[2-((R)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50073828(Benzyl-[2-((R)-2,2-dimethyl-1-methylcarbamoyl-prop...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed