BDBM50073819 3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-2-(diisopropoxy-phosphorylamino)-propionic acid::CHEMBL23200

SMILES CC(C)OP(=O)(NC(CNC(=O)CC1CC(=NO1)c1ccc(cc1)C(N)=N)C(O)=O)OC(C)C

InChI Key InChIKey=ATAGEZTYYUWRSG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073819   

TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50: 103nMAssay Description:Inhibition of platelet aggregation in citreated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50: 0.860nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50: 210nMAssay Description:Inhibition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50: 73nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed