BDBM50073794 CHEMBL367691::N*2*-(4-Amino-cyclohexyl)-N*6*-(3-chloro-phenyl)-9-ethyl-9H-purine-2,6-diamine

SMILES CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@H]3CC[C@H](N)CC3)nc12

InChI Key InChIKey=IKKPOUJRFXLTCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073794   

TargetCyclin-dependent kinase 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073794(N*2*-(4-Amino-cyclohexyl)-N*6*-(3-chloro-phenyl)-9...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed