BDBM50073703 2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[2,1-b]purin-4-one::CHEMBL416541

SMILES CCCCCCc1nc2N3CC(C)(C)N=C3N(C)C(=O)c2[nH]1

InChI Key InChIKey=PMEDQEVTXOFIQD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073703   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-GMP specific phosphodiesterase PDE5 of bovine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50: 25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50: 2.80E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed