BDBM50073132 (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-undecanoylamino]-3-phenyl-propionic acid ethyl ester::CHEMBL111745

SMILES CCCCCCCCC(NC(=O)c1ccc(cc1)C#N)C(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC

InChI Key InChIKey=PKBXRCQQXNGCNQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073132   

TargetChymase(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073132((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-undec...)
Affinity DataIC50: 6.20E+4nMAssay Description:Compound was tested by chromogenic assay for the inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073132((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-undec...)
Affinity DataIC50: 6.60E+3nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073132((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-undec...)
Affinity DataIC50: 8.60E+3nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073132((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-undec...)
Affinity DataIC50: 2.70E+3nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Porcine ElastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed