BDBM50073126 (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonanoylamino]-3-phenyl-propionic acid propyl ester::CHEMBL320132

SMILES CCCCCCC(NC(=O)c1ccc(cc1)C#N)C(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCCC

InChI Key InChIKey=PNWNVISGMUONQD-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50073126   

TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 270nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Porcine ElastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was tested by chromogenic assay for the inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 200nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataKi:  340nMAssay Description:Compound was evaluated for inactivation of bovine alpha-Chymotrypsin Kinetic constant(Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed