BDBM50073026 5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-6-phenyl-2H-pyridazin-3-one::CHEMBL301726

SMILES COc1ccccc1N1CCN(CCn2nc(-c3ccccc3)c(C(C)=O)c(N)c2=O)CC1

InChI Key InChIKey=HPKLBVVRBBCHTN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50073026   

TargetAlpha-1D adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073026(5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-pipera...)
Affinity DataKi:  0.930nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1D adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073026(5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-pipera...)
Affinity DataKi:  4.75nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073026(5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-pipera...)
Affinity DataKi:  22.1nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1B adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50073026(5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-pipera...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50073026(5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-pipera...)
Affinity DataKi:  123nMAssay Description:The compound was tested for binding affinity on [3H]8-OH-DPAT as specific ligand on 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed