BDBM50073025 8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one::CHEMBL301078

SMILES COc1ccccc1N1CCN(CCNc2ccc3c4c(cn3n2)c(Cl)nn(C)c4=O)CC1

InChI Key InChIKey=STIKULJYVCUQJQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073025   

TargetAlpha-1A adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073025(8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  1.10nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073025(8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.04nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1D adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50073025(8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  15.2nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1B adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50073025(8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  16.3nMAssay Description:The compound was tested for binding affinity on [3H]8-OH-DPAT as specific ligand on 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed