BDBM50072961 CHEMBL3410672

SMILES C[C@H]1COCCN1c1cc(nc(n1)-c1ccc(NC(=S)NCCO)cc1)C1(CC1)S(=O)(=O)C1CC1

InChI Key InChIKey=JWGVUDPAMQEIJU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50072961   

TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50: 912nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant PI3Kbeta (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of recombinant PI3Kdelta (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant PI3Kgamma (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed