BDBM50072959 CHEMBL3410535

SMILES [O-][N+](=O)c1ccc(\C=C2/CS(=O)(=O)C\C(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)cc1

InChI Key InChIKey=SSAMIOWVUGBIJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072959   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of GST-tagged UCHL5 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of USP2 catalytic domain (unknown origin) expressed in bacteria using Ub-AMC as substrate preincubated for 30 mins before substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetUbl carboxyl-terminal hydrolase 18(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of recombinant human USP18 (16 to 372 aa) expressed in Sf9 cells using ISG15-AMC as substrate preincubated for 30 mins before substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed