BDBM50072902 CHEMBL3410075

SMILES O=C(NC1CC1)c1ccc(cc1)-c1cnc2c(NCC3CCOCC3)cc(Oc3ccccc3)nn12

InChI Key InChIKey=BGJIRNOWWHDNHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072902   

TargetDual specificity protein kinase TTK(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072902(CHEMBL3410075)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of FLAG-tagged Mps1 autophosphorylation in human RERF-LC-AI cells expressing Tet-suppressible promotor after 3 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50072902(CHEMBL3410075)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Mps1 (unknown origin)-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed