BDBM50072865 CHEMBL55627::N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-3-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-((S)-4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid::N-[1-{1-[2-Carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-2-(4-phosphonomethyl-phenyl)-ethyl]-oxalamic acid

SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12

InChI Key InChIKey=LBUZYNYSEBMSDQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50072865   

TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 9nMAssay Description:Binding affinity for Growth factor receptor bound protein 2 SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 10nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity in ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth factor receptor-bound protein 2(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50072865(N-[1-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-prop...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding to p185erbB-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed