BDBM50072311 CHEMBL3408391

SMILES O=C1CS\C(=N/c2nc(cc(-c3ccccc3)c2C#N)-c2ccccc2)N1c1ccccc1

InChI Key InChIKey=MQAYCYSVHQWNLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072311   

TargetSerine/threonine-protein kinase Chk1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50072311(CHEMBL3408391)
Affinity DataIC50: 23nMAssay Description:Inhibition of CHK1 (unknown origin) using FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide substrate incubated for 1 hr by caliper microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50072311(CHEMBL3408391)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human ERG assessed as reduction in channel current expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed