BDBM50072303 CHEMBL3408383

SMILES CC(=O)c1nn(-c2ccccc2)\c(=N\c2nc(cc(-c3ccccc3)c2C#N)-c2ccccc2)s1

InChI Key InChIKey=JNXSRIBCMFBWQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072303   

TargetSerine/threonine-protein kinase Chk1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50072303(CHEMBL3408383)
Affinity DataIC50: 22nMAssay Description:Inhibition of CHK1 (unknown origin) using FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide substrate incubated for 1 hr by caliper microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50072303(CHEMBL3408383)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of human ERG assessed as reduction in channel current expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed