BDBM50072260 (Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid (0.2H2O)::CHEMBL22480

SMILES OC(=O)C(=O)CC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KKFZLKBJSYLDKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072260   

TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50: 6.40E+3nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed