BDBM50072203 2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2-thiophen-2-yl-quinazolin-7-yloxy]-ethanol::CHEMBL95979

SMILES COc1cc2c(nc(nc2cc1OCCO)-c1cccs1)-c1cc(OCC2CC2)cc(OCC2CC2)c1

InChI Key InChIKey=PUAYSZSGTRYVOR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072203   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072203(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)
Affinity DataIC50: 5.40E+3nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072203(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072203(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed