BDBM50072171 (1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-3-methyl-cyclopropanecarboxylic acid::CHEMBL97574

SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O

InChI Key InChIKey=VYTOVCNIMJIGDL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50072171   

TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 6.29E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 4 (mGluR4) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 2.31E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50072171((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed