BDBM50072080 CHEMBL3407919

SMILES OC(=O)c1cc(ncn1)-c1ccc(OC(F)(F)F)c(Cl)c1

InChI Key InChIKey=HSGCDKCENGBLPX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50072080   

TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 115nMAssay Description:Inhibition of KMO in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KMO in rat microglia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 11nMAssay Description:Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed