BDBM50072060 3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3']bipyridinyl::CHEMBL329120

SMILES Cc1cnc(-c2cccnc2)c(c1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=KJUCYHRLQYDCLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072060   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072060(3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3']bipyri...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of PGE-2 produced by arachidonic acid-stimulated CHO cells stably expressing human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072060(3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3']bipyri...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells incubated in low concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072060(3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3']bipyri...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 was measured by the inhibition of PGE-2 produced by lipopolysaccharide-challenged HWBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed