BDBM50072057 5-Chloro-3-(4-methanesulfonyl-phenyl)-5'-methyl-[2,3']bipyridinyl::CHEMBL96947

SMILES Cc1cncc(c1)-c1ncc(Cl)cc1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=LMVUBDIWWHZROU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072057   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072057(5-Chloro-3-(4-methanesulfonyl-phenyl)-5'-methyl-[2...)
Affinity DataIC50: 87nMAssay Description:In vitro inhibition of PGE-2 produced by arachidonic acid-stimulated CHO cells stably expressing human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072057(5-Chloro-3-(4-methanesulfonyl-phenyl)-5'-methyl-[2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells incubated in low concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50072057(5-Chloro-3-(4-methanesulfonyl-phenyl)-5'-methyl-[2...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 was measured by the inhibition of PGE-2 produced by lipopolysaccharide-challenged HWBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed