BDBM50071867 4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-pyrrol-3-yl]-pyridine::CHEMBL316275

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=GFYZFDVAKCDQST-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50071867   

TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of RAF kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Rat)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 9.80nMAssay Description:Inhibitory potency evaluated against rat p38 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071867(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of LPS-induced p38-related TNF alpha release from human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed