BDBM50071841 4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL327442

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1-c1ccccc1

InChI Key InChIKey=RWPUCYUUOPJZLU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071841   

TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071841(4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 116nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071841(4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071841(4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071841(4-(Biphenyl-2-carbonyl)-1-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed