BDBM50071838 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester::CHEMBL310655::tert-butyl 3-(hydroxycarbamoyl)-4-(4-methoxyphenylsulfonyl)-1,4-diazepane-1-carboxylate

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)OC(C)(C)C

InChI Key InChIKey=CTCOBJWAVVPWJG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50071838   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 26nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 618nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 618nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071838(3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed