BDBM50071834 4-(4-Methoxy-benzenesulfonyl)-[1,4]diazepane-1,3-dicarboxylic acid 3-hydroxyamide 1-phenylamide::CHEMBL313168::N3-hydroxy-4-(4-methoxyphenylsulfonyl)-N1-phenyl-1,4-diazepane-1,3-dicarboxamide

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)Nc1ccccc1

InChI Key InChIKey=APKANDPILBIUDO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071834   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071834(N3-hydroxy-4-(4-methoxyphenylsulfonyl)-N1-phenyl-1...)
Affinity DataIC50: 18nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071834(N3-hydroxy-4-(4-methoxyphenylsulfonyl)-N1-phenyl-1...)
Affinity DataIC50: 309nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071834(N3-hydroxy-4-(4-methoxyphenylsulfonyl)-N1-phenyl-1...)
Affinity DataIC50: 17nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50071834(N3-hydroxy-4-(4-methoxyphenylsulfonyl)-N1-phenyl-1...)
Affinity DataIC50: 17nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed