BDBM50071736 (S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-3-(1H-indol-3-yl)-2-methyl-2-[3-(4-nitro-phenyl)-ureido]-propionamide::CHEMBL85400

SMILES COc1ccc(cc1OC)C1(CNC(=O)[C@](C)(Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(cc2)[N+]([O-])=O)CCCCC1

InChI Key InChIKey=VFVKUZVSXDUHAQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071736   

TargetNeuromedin-B receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071736((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...)
Affinity DataKi:  0.440nMAssay Description:Antagonistic activity against labelled Bombesin receptor bb1 binding sites in rat olfactory bulb by using [125I]- [Tyr] bombesin in presence of [D-Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetGastrin-releasing peptide receptor(Human)
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071736((S)-N-[1-(3,4-Dimethoxy-phenyl)-cyclohexylmethyl]-...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed