BDBM50071710 1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[a,d]cyclohepten-5-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL423677

SMILES [O-][n+]1ccc(CC(=O)N2CCN(CC2)C2c3ccc(Cl)cc3SCc3cccnc23)cc1

InChI Key InChIKey=UBHOMARBJHLMPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071710   

LigandPNGBDBM50071710(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Ras processing in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50071710(1-[4-(8-Chloro-5,11-dihydro-10-thia-4-aza-dibenzo[...)
Affinity DataIC50: 79nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed