BDBM50071709 CHEMBL87345::Cyanoguanidine derivative

SMILES CN1Cc2cccnc2C(N2CCN(CC2)C(NCc2ccncc2)=NC#N)c2ccc(Cl)cc12

InChI Key InChIKey=ZMAIYSCOFUTXQH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071709   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50071709(Cyanoguanidine derivative | CHEMBL87345)Copy SMILESCopy InChI

Affinity DataIC50: 140nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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