BDBM50071703 CHEMBL311434::Cyanoguanidine derivative

SMILES [#8-]-[n+]1cccc(-[#6]-[#7]-[#6](=[#7]C#N)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2/c3ccc(Cl)cc3-[#16]-[#6]-c3cccnc-23)c1

InChI Key InChIKey=SJPPYNZAVPOAMK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071703   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50071703(Cyanoguanidine derivative | CHEMBL311434)Copy SMILESCopy InChI

Affinity DataIC50: 38nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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