BDBM50071699 CHEMBL313090::Cyanoguanidine derivative

SMILES Clc1ccc2C(N3CCN(CC3)C(NCc3ccncc3)=NC#N)c3ncccc3CSc2c1

InChI Key InChIKey=VLBFUKCAHIASOK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071699   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50071699(Cyanoguanidine derivative | CHEMBL313090)Copy SMILESCopy InChI

Affinity DataIC50: 61nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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