BDBM50071697 2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((2S,3S)-1-carbamimidoyl-2-hydroxy-piperidin-3-yl)-acetamide::CHEMBL79467

SMILES NC(=N)N1CCC[C@H](NC(=O)CN2CCC[C@@](N)(Cc3ccccc3)C2=O)[C@@H]1O

InChI Key InChIKey=MJWDBCUSOIFRIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50071697   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071697(2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50: 138nMAssay Description:In vitro inhibitory activity was evaluated against thrombin (FIIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071697(2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against human trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed